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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK5
All Species:
9.39
Human Site:
Y573
Identified Species:
18.79
UniProt:
Q6P3R8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P3R8
NP_954983.1
708
81445
Y573
S
K
N
P
E
Q
K
Y
K
A
K
K
G
V
K
Chimpanzee
Pan troglodytes
XP_001152651
708
81377
Y573
S
K
N
P
E
Q
K
Y
K
A
K
K
G
V
K
Rhesus Macaque
Macaca mulatta
XP_001103475
708
81434
Y573
S
K
N
P
E
Q
K
Y
K
P
K
K
G
V
K
Dog
Lupus familis
XP_856025
1241
141182
W743
V
S
S
D
R
K
K
W
E
A
G
G
Q
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSC3
627
71772
E499
D
G
Q
V
I
V
M
E
G
S
V
E
N
G
K
Rat
Rattus norvegicus
XP_001073521
655
74739
S527
L
A
I
E
R
A
C
S
G
S
L
S
A
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513277
864
98961
E576
H
E
N
A
A
G
E
E
M
E
N
D
T
L
N
Chicken
Gallus gallus
XP_417075
816
94076
A589
Y
E
G
P
M
E
R
A
L
G
D
L
S
G
Y
Frog
Xenopus laevis
Q7ZZC8
944
104521
L788
P
S
W
L
R
Q
E
L
E
E
A
E
F
I
P
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
E552
P
S
S
F
C
Q
V
E
E
V
H
L
F
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LT35
416
47232
G288
N
T
N
E
N
R
T
G
L
P
P
K
T
K
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
Q681
D
E
S
S
F
S
Q
Q
Q
N
N
Q
P
Q
Q
Conservation
Percent
Protein Identity:
100
99.2
96.1
27.5
N.A.
39.6
37.9
N.A.
47.7
36.4
22.3
24.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
97.4
40.5
N.A.
52.8
51.9
N.A.
61
51.9
39.7
41.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
13.3
N.A.
6.6
6.6
N.A.
6.6
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
46.6
N.A.
20
13.3
N.A.
26.6
26.6
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.7
N.A.
23
Protein Similarity:
N.A.
N.A.
N.A.
40.9
N.A.
41.7
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
9
9
0
9
0
25
9
0
9
0
0
% A
% Cys:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
0
9
0
0
0
0
0
0
9
9
0
0
0
% D
% Glu:
0
25
0
17
25
9
17
25
25
17
0
17
0
0
0
% E
% Phe:
0
0
0
9
9
0
0
0
0
0
0
0
17
0
0
% F
% Gly:
0
9
9
0
0
9
0
9
17
9
9
9
25
25
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
9
0
9
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
25
0
0
0
9
34
0
25
0
25
34
0
9
42
% K
% Leu:
9
0
0
9
0
0
0
9
17
0
9
17
0
17
9
% L
% Met:
0
0
0
0
9
0
9
0
9
0
0
0
0
0
0
% M
% Asn:
9
0
42
0
9
0
0
0
0
9
17
0
9
0
9
% N
% Pro:
17
0
0
34
0
0
0
0
0
17
9
0
9
0
9
% P
% Gln:
0
0
9
0
0
42
9
9
9
0
0
9
9
17
9
% Q
% Arg:
0
0
0
0
25
9
9
0
0
0
0
0
0
0
0
% R
% Ser:
25
25
25
9
0
9
0
9
0
17
0
9
9
0
9
% S
% Thr:
0
9
0
0
0
0
9
0
0
0
0
0
17
0
0
% T
% Val:
9
0
0
9
0
9
9
0
0
9
9
0
0
25
9
% V
% Trp:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
25
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _